------------------------------------------------------------------------------ SWISS-PROT Protein Sequence Data Bank. Release 36.0, July 1998 PROSITE Dictionary of Sites and Patterns in Proteins. Release 15.0, July 1998 ------------------------------------------------------------------------------ List of on-line experts for PROSITE and SWISS-PROT ------------------------------------------------------------------------------ Amos Bairoch Email: bairoch@medecine.unige.ch Swiss Institute of Bioinformatics and University of Geneva Switzerland ------------------------------------------------------------------------------ Document name: EXPERTS.TXT ------------------------------------------------------------------------------ Field of expertise Name Email address ---------------------------- ------------------ -------------------------------- 14-3-3 proteins Aitken A. a-aitken@nimr.mrc.ac.uk ABC transport membrane comp. Dassa E. elidassa@pasteur.fr ADP-ribosylation factors Kahn R.A. rkahn@bimcore.emory.edu Alcohol dehydrogenases Joernvall H. hans.jornvall@mbb.ki.se Persson B. bengt.persson@mbb.ki.se Aldehyde dehydrogenases Joernvall H. hans.jornvall@mbb.ki.se Persson B. bengt.persson@mbb.ki.se Alpha-crystallins/HSP-20 Leunissen J.A.M. jackl@caos.kun.nl de Jong W.W. w.dejong@bioch.kun.nl Alpha-2-macroglobulins Van Leuven F. fred@blekul13.bitnet Alpha-mannosidases Herscovics A. annette@medcor.mcgill.ca Aminotransferases Mehta P. jaimatadi@aeolus.ethz.ch Aminotransferases class V Ouzounis C. ouzounis@ebi.ac.uk AA-tRNA synthetases class II Cusack S. cusack@embl-grenoble.fr AraC family HTH proteins Ramos J.L. jlramos@samba.cnb.uam.es Gallegos M.-T. mtrini@samba.cnb.uam.es Arginases Ouzounis C. ouzounis@ebi.ac.uk Arrestins Kolakowski L.F.Jr. kolakowski@uthsca.edu Asparaginase / glutaminase Gribskov M. gribskov@sdsc.edu ATP synthase c subunit Recipon H. recipon@ncbi.nlm.nih.gov Avidin Flower D.R. darren.flower@charnwood.gb.astra.com Band 4.1 family proteins Rees J. jrees@vax.oxford.ac.uk Beta-lactamases Brannigan J. jab5@vaxa.york.ac.uk Bromo domain Aasland R. aasland@bio.uib.no BTG1 family Duret L. duret@biomserv.univ-lyon1.fr C1q domain Reid K.B.M. kbmreid@biochemistry.oxford.ac.uk C2 domain Hofmann K.O. khofmann@isrec-sun1.unil.ch C-type lectin domain Drickamer K. kd@glycob.ox.ac.uk Cadherins Pettitt J. pettitt@nki.nl Carboxylesterases type-B Sussman J. csjoel@weizmann.weizmann.ac.il Cathelicidins Tossi A. tossi@univ.trieste.it CBS domain Bateman A. agb@mrc-lmb.cam.ac.uk Chalcone/stilbene synthases Schroeder J. jschroe@sun2.ruf.uni-freiburg.de Chaperonins cpn10/cpn60 Georgopoulos C. georgopo@medecine.unige.ch Chaperonins TCP1 family Willison K.R. willison@icr.ac.uk Chitinases Neuhaus J.-M. jean-marc.neuhaus@bota.unine.ch Henrissat B. bernie@afmb.cnrs-mrs.fr Chromo domain Aasland R. aasland@bio.uib.no Clostridium cellul. repeat. Beguin P. beguin@pasteur.fr Clusterin Peitsch M.C. mcp13936@ggr.co.uk Coiled coil domains Lupas A.N. lupas@vms.biochem.mpg.de Cold shock domain Landsman D. landsman@ncbi.nlm.nih.gov Crystallins beta/gamma Wistow G. graeme@helix.nih.gov CTF/NF-I Mermod N. nmermod@ulys.unil.ch Gronostajski R. gronosr@ccsmtp.ccf.org CUB domain Bork P. bork@embl-heidelberg.de Cuticle proteins Roepstorff P. roe@pr-group.ou.dk Cytochrome c oxidase Saraste M. saraste@embl-heidelberg.de Cytochromes P450 Degtyarenko K.N. kirill@icgeb.trieste.it Cytosolic fatty acid bind. Flower D.R. darren.flower@charnwood.gb.astra.com DEAD-box helicases Linder P. linder@medecine.unige.ch Death domain Hofmann K.O. khofmann@isrec-sun1.unil.ch Deoxyribonuclease I Peitsch M.C. mcp13936@ggr.co.uk Dichloromethane dehalogenase Vuilleumier S. svuilleu@micro.biol.ethz.ch dnaJ family Kelley W. kelley@medecine.unige.ch DNA/RNA non-spec. nucleases Friedhoff P. friedhoff@mpasmb.desy.de EF-hand calcium-binding Cox J.A. cox@sc2a.unige.ch Kretsinger R.H. rhk5i@virginia.edu EGF-like domain, Ca++ Downing A.K. kristy@bioch.ox.ac.uk Elongation factor 1 Amons R. wmbamons@rulgl.leidenuniv.nl Enoyl-CoA hydratase Hofmann K.O. khofmann@isrec-sun1.unil.ch Ependymins Hoffmann W. werner.hoffmann@medizin.uni-magdeburg.de Fatty acid desaturases Piffanelli P. piffanelli@jii.afrc.ac.uk Fibrinogens Doolittle R.F. rdoolittle@ucsd.edu Fibronectin type III Beckmann G. beckmann@bioinf.mdc-berlin.de Bork P. bork@embl-heidelberg.de Fimbrial usher proteins Schifferli D.M. dmschiff@pobox.upenn.edu FKBP-type Ppiase Callebaut I. isabelle.callebaut@lmcp.jussieu.fr Follistatin domain Patthy L. patthy@enzim.hu Forkhead-associated domain Hofmann K.O. khofmann@isrec-sun1.unil.ch fruR/lacI family HTH proteins Reizer J. jreizer@ucsd.edu GltP family of transporters Hofmann K.O. khofmann@isrec-sun1.unil.ch Glucanases Henrissat B. bernie@afmb.cnrs-mrs.fr Beguin P. phycel@pasteur.fr Glutamine synthetase Tateno Y. ytateno@genes.nig.ac.jp Glycerol-3-P dehydr. FAD Brown L.J. ljbrown2@facstaff.wisc.edu Glycoprotease family Lo R.Y.C. rlo@uoguelph.ca Glycoprotein hormones Lapthorn A. adrian@chem.gla.ac.uk Glycosyl hydrolases Henrissat B. bernie@afmb.cnrs-mrs.fr Glycosyl transferases (Euk.) Wilson I. wilson@edv1.boku.ac.at G-proteins Pennington S.R. srpenn@liverpool.ac.uk G-protein coupled receptors Attwood T.K. attwood@bsm.bioc.ucl.ac.uk Kolakowski L.F.Jr. kolakowski@uthsca.edu grpE family Georgopoulos C. georgopo@medecine.unige.ch Hematopoietins (Interleukins) Boulay J.-L. boulay@ubaclu.unibas.ch HIT family Seraphin B. seraphin@embl-heidelberg.de Aitken A. a-aitken@nimr.mrc.ac.uk HMG1/2 and HMG-14/17 Landsman D. landsman@ncbi.nlm.nih.gov Homeobox domain Buerglin T.R. burglin@ubaclu.unibas.ch Hyaluronan binding domain Barta E. barta@hubi.abc.hu IGF binding proteins Landale E.C. elandale@biotechnet.com Inorganic pyrophosphatases Kolakowski L.F.Jr. kolakowski@uthsca.edu Integrases Roy P.H. proy@rsvs.ulaval.ca Interferons Rubinstein M. lvrub@wiccmail.weizmann.ac.il Interleukin-6 family Rose-John S. rose@mzdmza.zdv.uni-mainz.de Kringle domain Ikeo K. kikeo@genes.nig.ac.jp Laminins Maurer P. maurer2@urz.unibas.ch LBP / BPI / CETP family Jongeneel C.V. victor.jongeneel@isrec.unil.ch Lipocalins Peitsch M.C. mcp13936@ggr.co.uk Flower D.R. darren.flower@charnwood.gb.astra.com Lipolytic enz. 'G-D-S-L' Upton C. upton@sol.uvic.ca Buckley J.T. tbuckley@sol.uvic.ca lysR family HTH proteins Schell M. schell@uga.cc.uga.edu MAC components / perforin Peitsch M.C. mcp13936@ggr.co.uk Malic enzymes Glynias M. mglynias@ncsa.uiuc.edu MAM domain Bork P. bork@embl-heidelberg.de MAP and Tau proteins Matus A. matus@fmi.ch marR family HTH proteins Robison K. robison@mpi.com Metallothioneins Binz P.-A. binz@dim.hcuge.ch MHC complex proteins Marsh S.G.E. s_marsh@icrf.icnet.uk MIP family proteins Reizer J. jreizer@ucsd.edu Myelin proteolipid protein Hofmann K.O. khofmann@isrec-sun1.unil.ch Nitrate reductases Rouze P. pirou@gengenp.rug.ac.be Odorant receptors Lancet D. bmlancet@weizmann.weizmann.ac.il OmpA-like domain De Mot R. Rene.DeMot@agr.kuleuven.ac.be Osteonectins Maurer P. maurer2@urz.unibas.ch P-type domain Hoffmann W. werner.hoffmann@medizin.uni-magdeburg.de Pancreatic trypsin inhibitor Ikeo K. kikeo@genes.nig.ac.jp PEP requiring enzymes Reizer J. jreizer@ucsd.edu Peptidases Rawlings N. neil.rawling@bbsrc.ac.uk Pertussis toxin Raupach B. raupach@cmgm.stanford.edu pfkB carbohydrate kinases Reizer J. jreizer@ucsd.edu PH domain Gibson T.J. gibson@embl-heidelberg.de PI domain (PID) Bork P. bork@embl-heidelberg.de Margolis B. margolisb@mcphm0.med.nyu.edu Phosphatidyleth.-binding Schoentgen F. schoent@cnrs-orleans.fr Phospholipase A2 Seilhamer J.J. jeff@incyte.com Phosphomannose isomerases Proudfoot A.E.I. aep6830@ggr.co.uk Phytochromes Partis M.D. mickp@hotmail.com Plant viruses icos. capsid Koonin E.V. koonin@ncbi.nlm.nih.gov Poly (ADP-ribose) polymerase Kappus S. kappus@ebi.ac.uk Protein kinases Quinn A.M. quinn@biomed.med.yale.edu Hunter T. hunter@salk-sc2.sdsc.edu Protein phosphatase 2A Hemmings B.A. hemmings@fmi.ch PTR2 oligopeptide symporters Steiner H.-Y. steinerh@am.abru.cg.com Becker J.M. jbecker@utkvx.utk.edu PTS proteins Reizer J. jreizer@ucsd.edu Reaction center proteins Edelman M. lpedel@weizmann.weizmann.ac.il Hirschberg J. hirschu@hujivms.huji.ac.il RecA Roca A.I. roca@macc.wisc.edu Eisen J.A. jeisen@leland.stanford.edu RecR Roca A.I. roca@macc.wisc.edu Release factors Tate W.P. wptate@sanger.otago.ac.nz Restriction-modif. enzymes Bickle T. bickle@ubaclu.unibas.ch Roberts R.J. roberts@neb.com Ribosomal protein S6e Thomas G. gthomas@fmi.ch Ribosomal protein S15 Ellis S.R. srelli01@ulkyvm.bitnet Ribosomal protein S19e Bernard V. vincent.bernard@unifr.ch Ring-cleavage dioxygenases Harayama S. sharayam@ddbj.nig.ac.jp RNA 3'-terminal P cyclases Filipowicz W. filipowi@fmi.ch RTX toxins Frey J. jfrey@vbi.unibe.ch S-layer homology domain Lupas A.N. lupas@vms.biochem.mpg.de SH2 domain Zvelebil M. marketa@ludwig.ucl.ac.uk SH3 domain Zvelebil M. marketa@ludwig.ucl.ac.uk Sigma-70 factors ECF subf. Rudd K.E. rudd@ecogene.med.miami.edu Signal sequence peptidases von Heijne G. gunnar@biokemi.su.se Dalbey R.E. rdalbey@magnus.acs.ohio-state.edu SNF2 family of helicases Eisen J.A. jeisen@leland.stanford.edu Sodium symporters Reizer J. jreizer@ucsd.edu Somatomedin B domain Jenne D. djenne@ulys.unil.ch Subtilases Brannigan J. jab5@vaxa.york.ac.uk Siezen R.J. siezen@nizo.nl Syndecans Spring J. spring@ubaclu.unibas.ch tetR family HTH proteins Robison K. robison@mpi.com Thiol proteases, C1-type Turk B. boris.turk@ijs.si Thiol proteases RNA viruses Margis R. margisr@chagas.biof.ufrj.br Thiol proteases inhibitors Turk B. boris.turk@ijs.si TNF family Jongeneel C.V. victor.jongeneel@isrec.unil.ch Transglycosylases Dijkstra A.J. arnoud_jan.dijkstra@roche.com Transit peptides von Heijne G. gunnar@biokemi.su.se Transposases, Mutator family Eisen J.A. jeisen@leland.stanford.edu Transcription factor TFIIB Ouzounis C. ouzounis@ebi.ac.uk Transcription factors Wingender E. ewi@gbf-braunschweig.de Transmembrane 4 family Levy S. levy@cellbio.stanford.edu Wright M.D. wright_m@wehi.edu.au Ubiquitin-conjugating enzymes Jentsch S. jentsch@zmbh.uni-heidelberg.de Uracil-DNA glycosylase Aasland R. aasland@bio.uib.no Vitamin K-depend. Gla domain Price P.A. pprice@ucsd.edu von Willebrand factor type A Bachrati C.S. csanad@rosi.szbk.u-szeged.hu von Willebrand factor type C Bork P. bork@embl-heidelberg.de XPG protein Clarkson S.G. clarkson@medecine.unige.ch Xylose isomerase Jenkins J. jenkins@frira.afrc.ac.uk WAP-type domain Claverie J.-M. jmc@ir1cbm.cnrs-mrs.fr WW/rsp5/WWP domain Bork P. bork@embl-heidelberg.de Sudol M. m_sudol@smtplink.mssm.edu Zinc finger, C2H2 type Becker K.G. teeber@helix.nih.gov ZP domain Bork P. bork@embl-heidelberg.de African swine fever virus Yanez R.J. r.yanez@rpms.ac.uk Bacteriophage P4 Halling C. chh9@midway.uchicago.edu Bacteriophage T4 Kutter E. t4phage@u.washington.edu Bacillus subtilis Moszer I. moszer@pasteur.fr Caenorhabditis elegans Sonnhammer E.L.L. esr@sanger.ac.uk Chlamydia trachomatis Ratti G. ratti@iris02.biocine.it Chloroplast encoded proteins Hallick R.B. hallick@arizona.edu Dictyostelium discoideum Smith D.W. dsmith@ucsd.edu Drosophila Ashburner M. ma11@phx.cam.ac.uk Drosophila nuclear proteins Jacq B. jacq@lgpd.univ-mrs.fr Erwinia chrysanthemi Barras F. barras@ibsm.cnrs-mrs.fr Escherichia coli Rudd K.E. rudd@ecogene.med.miami.edu Hydra Bosch T.C.G. bosch@zi.biologie.uni-muenchen.de Mycobacterium leprae Robison K. keith_robison@msmail.mpi.com Pseudomonas Harayama S. sharayam@ddbj.nig.ac.jp Saccharomyce cerevisiae Linder P. linder@medecine.unige.ch Salmonella typhimurium Rudd K. rudd@ecogene.med.miami.edu Snakes Stocklin R. stocklin@medecine.unige.ch Sulfolobus solfataricus Sensen C.W. sensencw@niji.imb.nrc.ca Human EST derived sequences Houlgatte R. houlgatt@isagrogn.vjf.inserm.fr Requirements to fulfill to become an on-line expert =================================================== An expert should be a scientist working with specific famili(es) of proteins (or specific domains) and who would: a) Review the protein sequences in SWISS-PROT and the patterns/matrices in PROSITE relevant to their field of research. b) Agree to be contacted by people that have obtained new sequence(s) which seem to belong to "their" familie(s) of proteins. c) Have access to electronic mail and be willing to use it to send and receive data. If you are willing to be part of this scheme please contact me (but, please by email exclusively !) +-----------------------------+---------------------------------------------+ | Amos Bairoch | Email: bairoch@medecine.unige.ch | | Dept. Medical Biochemistry +---------------------------------------------+ | C.M.U. | Tel : +(41 22) 702 54 77 | | 1, rue Michel Servet +---------------------------------------------+ | 1211 Geneva 4 | Fax : +(41 22) 702 55 02 | | Switzerland | | +-----------------------------+---------------------------------------------+